What makes tissues rigid of fluid?
Regulation of the actin cytoskeleton and catherin-based cell adhesion.
The general goal of our project is to understand the cellular mechanisms that confer tissues with specific properties to tissues.
We focus on the role of the actin cytoskeleton in regulating motility and adhesion within embryonic tissues, focusing on the role of the cytoskeleton. We use the ectoderm and the mesoderm of Xenopus embryos as tissue prototypes: the former is stiff, cohesive and static, the latter is loose and highly dynamic.
We are looking for an outstanding candidate interested in the fields of Cell Biology. His/her project will focus on studying the role specific regulators of the cytoskeleton using of molecular and cell biology approaches.