• 2023 : The CRBM is recruiting new group leaders

    CRBM : Center for Research in cell Biology of Montpellier

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  • Functional analysis of Wolbachia Cid effectors unravels cooperative interactions to target host chromatin during replication

    Team Landmann, PLOS Pathogens 2023

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  • Pathogenic TRIO variants associated with neurodevelopmental disorders perturb the molecular regulation of TRIO and axon pathfinding in vivo

    Team Debant, Molecular Psychiatry 2023

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  • The Syp1/FCHo2 protein induces septin filament bundling through its intrinsically disordered domain

    Team Piatti, Cell Report 2022

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  • The Difference in Structural States between Canonical Proteins and Their Isoforms Established by Proteome-Wide Bioinformatics Analysis.

    Team KAJAVA, Biomolecules 2022

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  • congratulation to DR Albert TSAI who will join the CRBM Feb 1st 2023 as a new atip team leader fellow of the Fondation Bettencourt Schueller

    Team TSAI, ATIP 2022

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  • Oncogenic Signalling of PEAK2 Pseudokinase in Colon Cancer

    Team Roche, Cancers (Basel) 2022

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  • Nuclear ingression of cytoplasmic bodies accompanies a boost in autophagy.

    Team Moriel-Carretero, Life Science Alliance 2022

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  • 40 years ago, in January 1982, The EMBO Journal published its very first issue. On this occasion, we look back at noteworthy articles published in the journal over the years, reflecting the shifting areas of research under the broadest definition of ‘molecular biology’.

    Team Castro/Lorca
    Greatwall maintains mitosis through regulation of PP2A
    The EMBO Journal (2009)28:2786-2793

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  • Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition.

    Team Blangy/Gauthier-Rouvière, Journal of Cell Science 2022

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  • The TRRAP transcription cofactor represses interferon-stimulated genes in colorectal cancer cells

    Team Helmlinger, Elife 2022

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The CRBM hosts 18 research teams

Anne BLANGY & Cécile GAUTHIER-ROUVIÈRE

Cytoskeleton and membrane trafficking dynamics in cellular adhesion

Anna CASTRO & Thierry LORCA

Phosphatases in cell cycle and signaling

Alenka COPIC

Cell biology of lipid storage and transfer

Anne DEBANT

Signalling and cytoskeleton dynamics

Bénédicte DELAVAL

Centrosome, cilia and pathologies

Francois FAGOTTO

Cell adhesion and migration in embryonic development

Dominique HELMLINGER

Regulation of gene expression

Andrey KAJAVA

Structural bioinformatics and molecular modelling

Frédéric LANDMANN

Mechanisms of symbiosis with Wolbachia

Patrick LEMAIRE

Transcriptional control of chordate morphogenesis

Dimitris LIAKOPOULOS

Spindle positioning and organization

María MORIEL-CARRETERO

Cytoplasmic control of genome stability

Simonetta PIATTI

Mitotic regulation of chromosome partitioning and cell division

Claude PRIGENT

Cell Cycle

Serge ROCHE

Cancer cell signaling

Albert TSAI

Nuclear organization of transcription in embryos

Dimitris XIRODIMAS

Ubiquitin/Ubiquitin-like molecules and Protein Quality Control

Pierre ROUX

Team R&D :
Dynamics of cell invasion in cancer

In few numbers

160

people

40%

of the group leaders
are women

15

Different
Nationalities

24

Pathologies
studied

Montpellier Cell Biology Research Center

The CRBM has acquired its credentials in particular through the “cell cycle” theme, which has made the laboratory internationally renowned thanks to the discovery of the molecular mechanisms that control cell division with the work initiated by Marcel Dorée and his team.
This theme is still extremely active at the CRBM, and the research projects developed aim at understanding the molecular mechanisms governing mitosis, under normal conditions or during tumorigenesis.

The CRBM, this is also