• Financement 2023: Congratulations to the 9 award-winning researchers

    FRM : Patrick Lemaire, Simonetta Piatti, Serge Roche
    INCa : Daniel Bouvard, Dom Helmlinger, Serge Roche
    ANR : Anna Castro, Anne Blangy, Alenka Copic

  • The structure of the NuA4–Tip60 complex reveals the mechanism and importance of long-range chromatin modification

    Team Helmlinger, Nature Structural & Molecular Biology 2023

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  • A sterol-PI(4)P exchanger modulates the Tel1/ATM axis of the DNA damage response

    Equipe Moriel-Carretero, EMBO Journal 2023

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  • The motor domain of the kinesin Kip2 promotes microtubule polymerization at microtubule tips

    Team Liakopoulos, Journal of Cell Biology 2023

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  • A structural biology community assessment of AlphaFold2 applications.

    Equipe KAJAVA, Nature Structural and Molecular Biology 2022

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  • Targeting the NEDP1 enzyme to ameliorate ALS phenotypes through stress granule disassembly

    Equipe Xirodimas, Science Advances 2023

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  • Functional analysis of Wolbachia Cid effectors unravels cooperative interactions to target host chromatin during replication

    Team Landmann, PLOS Pathogens 2023

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  • Pathogenic TRIO variants associated with neurodevelopmental disorders perturb the molecular regulation of TRIO and axon pathfinding in vivo

    Team Debant, Molecular Psychiatry 2023

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  • The Syp1/FCHo2 protein induces septin filament bundling through its intrinsically disordered domain

    Team Piatti, Cell Report 2022

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  • The Difference in Structural States between Canonical Proteins and Their Isoforms Established by Proteome-Wide Bioinformatics Analysis.

    Team KAJAVA, Biomolecules 2022

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  • congratulation to DR Albert TSAI who will join the CRBM Feb 1st 2023 as a new atip team leader fellow of the Fondation Bettencourt Schueller

    Team TSAI, ATIP 2022

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  • Oncogenic Signalling of PEAK2 Pseudokinase in Colon Cancer

    Team Roche, Cancers (Basel) 2022

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  • Nuclear ingression of cytoplasmic bodies accompanies a boost in autophagy.

    Team Moriel-Carretero, Life Science Alliance 2022

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The CRBM hosts 18 research teams

Anne BLANGY & Cécile GAUTHIER-ROUVIÈRE

Cytoskeleton and membrane trafficking dynamics in cellular adhesion

Anna CASTRO & Thierry LORCA

Phosphatases in cell cycle and signaling

Alenka ČOPIČ

Cell biology of lipid storage and transfer

Anne DEBANT

Signalling and cytoskeleton dynamics

Bénédicte DELAVAL

Centrosome, cilia and pathologies

Francois FAGOTTO

Cell adhesion and migration in embryonic development

Dominique HELMLINGER

Regulation of gene expression

Andrey KAJAVA

Structural bioinformatics and molecular modelling

Frédéric LANDMANN

Mechanisms of symbiosis with Wolbachia

Patrick LEMAIRE

Transcriptional control of chordate morphogenesis

Dimitris LIAKOPOULOS

Spindle positioning and organization

María MORIEL-CARRETERO

Cytoplasmic control of genome stability

Simonetta PIATTI

Mitotic regulation of chromosome partitioning and cell division

Claude PRIGENT

Cell Cycle

Serge ROCHE

Cancer cell signaling

Albert TSAI

Nuclear organization of transcription in embryos

Dimitris XIRODIMAS

Ubiquitin/Ubiquitin-like molecules and Protein Quality Control

Pierre ROUX

Team R&D :
Dynamics of cell invasion in cancer

In few numbers

160

people

40%

of the group leaders
are women

15

Different
Nationalities

24

Pathologies
studied

Montpellier Cell Biology Research Center

The CRBM has acquired its credentials in particular through the “cell cycle” theme, which has made the laboratory internationally renowned thanks to the discovery of the molecular mechanisms that control cell division with the work initiated by Marcel Dorée and his team.
This theme is still extremely active at the CRBM, and the research projects developed aim at understanding the molecular mechanisms governing mitosis, under normal conditions or during tumorigenesis.

The CRBM, this is also